On December 22, the US Food and Drug Administration approved Paxlovid, the first prescription antiviral drug in tablet form for the treatment of mild to moderate Covid-19 cases.
Paxlovid produced by Pfizer should be taken “as soon as possible” after the diagnosis of Covid-19 and within five days of the onset of symptoms.
Dr. Patrizia Cavazzoni, Director of the Evaluation and Research Center, said: “Today’s license introduces the first treatment for Covid-19 in the form of oral tablets-this is an important step forward in the fight against the pandemic. Translation. This Global translation.” FDA drug review, statement. “When new variants emerge at critical moments of the pandemic, this provides a new tool to combat Covid-19 and is expected to make antiviral treatments easier for those at high risk of severe Covid-19.”
What are the ingredients of Paxlowi?
Paxlovid has two main ingredients-nimaravir and ritonavir. These ingredients work together on the protein of SARS-CoV-2, the virus that causes Covid-19. Nirmatrelvir prevents virus replication, and ritonavir slows down the breakdown of nirmatrelvir, helping it stay in the body longer at higher concentrations.
What does Parkslowed do?
Paxlovid is not a preventive or therapeutic drug. In other words, you should not take medication to prevent Covid-19 infection or after contact with an infected person. For people who need to be hospitalized due to severe Covid-19 disease, the drug should not be considered as first-line treatment.
Instead, the drug will be given to people who have tested positive for Covid-19 and are considered at risk of serious complications from the virus. Once administered, the drug helps prevent SARS-CoV-2 from multiplying in the body. William Schaffner, MD, an infectious disease expert at Vanderbilt University School of Medicine, explained that the virus cannot replicate, so the virus does not infect people or cause only mild symptoms. compare.
In a press release regarding Paxlovid’s license, the FDA emphasized that the drug cannot replace vaccination and booster doses.
The drug used to treat Covid-19 is provided in a course of 30 tablets, taken 2 times a day, 3 tablets each time for 5 days.
What is the price of Paxlow?
Paxlovid costs US$530 for a course of treatment. But in the United States, the cost of treatment is borne by the government and is free to the public.
Does Paxlovid interact with other drugs?
Yes-and a lot. A complete list of over 100 possible drug interactions. However, in general, Paxlovid interacts with many drugs, including heart drugs, some antibiotics, some anticonvulsants, and some statins.
Who does Paxlovid apply to?
The exact list can only be provided after the drug has been approved by the Centers for Disease Control and Prevention (CDC), but the FDA stated that Paxlovid is only applicable to “adults and pediatric patients-12 years and older weighing at least 40 kg-SARS-CoV- 2 People who have tested positive and are at high risk of severe Covid-19 disease (including hospitalization or death).
When can people use Paxlovid?
This may take some time, at least a few months. However, in general, doctors are happy to have another tool to help fight Covid-19, especially when two-thirds of monoclonal antibody treatments are found to be ineffective. Effective. Effective. The result of Omicron conversion.